to understand what cellular proteins do and how

The publication of the human genome in February 2001 has provided a directory of genes. Still, how proteins work in cells have yet to be elucidated.

Indeed, proteins are the products of gene expression and the active components of cellular function. Understanding what proteins do and how is the next major step in life sciences: a caterpillar and its butterfly phase both contain the same genome but express 2 different proteomes!

Hybrigenics Services propose services aiming at understanding how proteins work by elucidating how proteins interact with one another. Protein function is indeed universally carried through interaction with other proteins whether in cell signalling, cell metabolism, protein degradation, biochemical and structural complexes… and even in the case of catalytic activities, proteins substrates often contain docking sites for enzymes.

Hybrigenics Services also offer a Small Molecule Screening service to use protein interactions as pharmaceutical, cosmetic or agronomic targets to identify small molecules that would inhibit them.